Brothers: A Tale of Two Sons is a video game played by Venturian on the Xbox Live Arcade. The player (Venturian) controls both sons, Big Brother (named Tom by Venturian) and Little Brother (named Jerry by Venturian), while searching for their father's medicine.
In a faraway land, we see a flashback of a boy (Jerry, Little Brother) and his mother out in the water in a boat. The mother is drowning, and the boy can do nothing to help. The boy is seen kneeling at his mother's grave, when all of a sudden, the other brother (Tom, Big Brother) runs and gets him; their father is sick.